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Invitrogen
AIM2 Polyclonal Antibody
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FIGURE: 1 / 3
AIM2 Antibody (PA5-26874) in ICC/IF
Immunocytochemistry analysis of AIM2 in MCF-7 cells. Samples were incubated in AIM2 polyclonal antibody (Product # PA5-26874) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-26874
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human AIM2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RP11-520H16.3; unnamed protein product
Gene Aliases: PYHIN4
UniProt ID: (Human) O14862
Entrez Gene ID: (Human) 9447
activation of innate immune response
pattern recognition receptor signaling pathway
positive regulation of defense response to virus by host
immune response
cellular response to DNA damage stimulus
brain development
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
T cell homeostasis
positive regulation of inflammatory response
regulation of behavior
defense response to virus
negative regulation of protein kinase B signaling
neuron cellular homeostasis
pyroptosis
cellular response to cytokine stimulus
cellular response to xenobiotic stimulus
AIM2 inflammasome complex assembly
pyroptosome complex assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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