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Invitrogen
RAN Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-29926
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Amphibian,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RAN. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.6 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HeLa, Mouse testis.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (97%), Drosophila (95%), Dog (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: androgen receptor-associated protein 24; ARA25; G protein; G protein; RAN/TC4; ARA24; GTP-binding protein; GTPase Ran; guanosine triphosphatase Ran; member RAS oncogene family; OTTHUMP00000166078; OTTHUMP00000166102; RAN; RanGTPase; ras-like protein; ras-like protein TC4; ras-related nuclear protein; unnamed protein product
Gene Aliases: ARA24; Gsp1; TC4
UniProt ID: (Human) P62826, (Mouse) P62827
Entrez Gene ID: (Human) 5901, (Mouse) 19384
magnesium ion binding
chromatin binding
RNA binding
GTPase activity
obsolete small monomeric GTPase activity
nuclear export signal receptor activity
protein binding
GTP binding
GDP binding
cadherin binding
protein heterodimerization activity
pre-miRNA binding
protein domain specific binding
macromolecular complex binding
dynein intermediate chain binding
importin-alpha family protein binding
ribosomal subunit export from nucleus
ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
mitotic sister chromatid segregation
mitotic cell cycle
DNA metabolic process
protein import into nucleus
protein export from nucleus
nucleocytoplasmic transport
mitotic spindle organization
viral process
pre-miRNA export from nucleus
positive regulation of protein import into nucleus
GTP metabolic process
snRNA import into nucleus
protein localization to nucleolus
glycolytic process
protein localization
actin cytoskeleton organization
protein complex localization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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