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Invitrogen
VDP Polyclonal Antibody
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Product Details
PA5-30281
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human VDP/p115. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3, mouse liver.
Predicted reactivity: Human (99%), Mouse (94%), Rat (93%), Chicken (88%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: General vesicular transport factor p115; Protein USO1 homolog; TAP; transcytosis associated protein; transcytosis associated protein p115; Transcytosis-associated protein; unnamed protein product; USO1 homolog, vesicle docking protein; USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein p115; vesicle docking protein, 115 kDa; Vesicle-docking protein
Gene Aliases: 115kDa; P115; TAP; USO1; VDP
UniProt ID: (Human) O60763, (Mouse) Q9Z1Z0
Entrez Gene ID: (Human) 8615, (Mouse) 56041
intracellular protein transport
ER to Golgi vesicle-mediated transport
Golgi organization
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
secretory granule localization
transcytosis
Golgi vesicle transport
Golgi vesicle docking
vesicle fusion with Golgi apparatus
membrane fusion
regulation of cellular response to insulin stimulus
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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