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Invitrogen
Mig-6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-31137
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Mig-6. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.29 mg/mL
Amount
29 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HCT116.
Predicted reactivity: Rhesus Monkey (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ERBB receptor feedback inhibitor 1; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog
Gene Aliases: 1300002F13Rik; AI788755; ERRFI1; Mig-6; MIG6; RALT
UniProt ID: (Mouse) Q99JZ7
Entrez Gene ID: (Mouse) 74155
negative regulation of epidermal growth factor-activated receptor activity
stress-activated protein kinase signaling cascade
negative regulation of protein autophosphorylation
negative regulation of interleukin-1 beta production
negative regulation of collagen biosynthetic process
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tumor necrosis factor biosynthetic process
skin morphogenesis
regulation of keratinocyte differentiation
lung alveolus development
negative regulation of peptidyl-tyrosine phosphorylation
lung vasculature development
lung epithelium development
regulation of type B pancreatic cell proliferation
negative regulation of ERK1 and ERK2 cascade
negative regulation of cardiac muscle hypertrophy in response to stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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