Search
Invitrogen
LRRC4C Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-31873
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human Netrin G1 ligand. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, mouse brain, rat brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Leucine-rich repeat-containing 4C (LRRC4C), also known as Netrin-G ligand 2 (NGL-2), is a gene highlighted for its expression in the nervous system, particularly the brain. It is a member of the leucine-rich repeat superfamily, which plays a significant role in cell adhesion and signaling pathways critical for synaptic connectivity and neuronal development. LRRC4C is involved in neural processes such as axon guidance and synapse formation, aiding in the establishment of functional neural circuits. Additionally, research has suggested that LRRC4C may function as a tumor suppressor, particularly in gliomas, indicating its potential role in neuro-oncological disorders. Variations or deletions in this gene have been linked to neurodevelopmental disorders, demonstrating its importance in normal brain function and development. Furthermore, LRRC4C's expression patterns and associations with cancer also suggest its potential as a prognostic marker in clinical settings.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: netrin-G ligand-1; netrin-G1 ligand; unnamed protein product
Gene Aliases: 6430556C10Rik; NGL-1; NGL1; RGD1311013
UniProt ID: (Human) Q9HCJ2, (Mouse) Q8C031
Entrez Gene ID: (Human) 57689, (Mouse) 241568, (Rat) 311236
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support