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Invitrogen
CD70 Polyclonal Antibody
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Product Details
PA5-32701
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 17 amino acid peptide from N-terminus of human CD70.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon (94%) Monkey (88%).
Target Information
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD27 ligand; CD27-L; CD70; CD70 antigen; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand 8A; Tumor necrosis factor ligand superfamily member 7; type II transmembrane protein; unnamed protein product
Gene Aliases: CD27-L; CD27L; CD27LG; CD70; LPFS3; TNFSF7; TNLG8A
UniProt ID: (Human) P32970
Entrez Gene ID: (Human) 970
T cell mediated immunity
immune response
B cell mediated immunity
tumor necrosis factor-mediated signaling pathway
T cell proliferation
B cell proliferation
positive regulation of T cell proliferation
T cell activation
lymphocyte proliferation
adaptive immune memory response involving T cells and B cells
extrinsic apoptotic signaling pathway
CD27 signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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