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Invitrogen
Adenosine Deaminase Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-34661
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Adenosine Deaminase. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Raji, NCI-H929.
Predicted reactivity: Mouse (85%), Rat (84%), Bovine (89%).
IHC notes, Requires antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ada; adenosine aminohydrolase; adenosine deaminase (EC 3.5.4.4); RP11-61L14.5; unnamed protein product
Gene Aliases: ADA1
UniProt ID: (Human) P00813, (Rat) Q920P6, (Mouse) P03958
Entrez Gene ID: (Human) 100, (Rat) 24165, (Mouse) 11486
response to hypoxia
adenosine catabolic process
AMP catabolic process
xenobiotic metabolic process
purine ribonucleoside monophosphate biosynthetic process
response to purine-containing compound
purine nucleotide salvage
GMP salvage
regulation of cell-cell adhesion mediated by integrin
T cell activation
purine-containing compound salvage
hypoxanthine salvage
AMP salvage
regulation of circadian sleep/wake cycle, sleep
dAMP catabolic process
adenosine metabolic process
inosine biosynthetic process
negative regulation of adenosine receptor signaling pathway
in utero embryonic development
histamine secretion
trophectodermal cell differentiation
liver development
placenta development
germinal center B cell differentiation
positive regulation of germinal center formation
negative regulation of leukocyte migration
negative regulation of mature B cell apoptotic process
deoxyadenosine catabolic process
response to xenobiotic stimulus
positive regulation of heart rate
lung development
positive regulation of B cell proliferation
regulation of T cell differentiation in thymus
positive regulation of T cell differentiation in thymus
response to vitamin E
negative regulation of circadian sleep/wake cycle, non-REM sleep
response to hydrogen peroxide
negative regulation of apoptotic process
regulation of T cell differentiation
positive regulation of T cell differentiation
positive regulation of smooth muscle contraction
dATP catabolic process
hypoxanthine biosynthetic process
xanthine biosynthetic process
positive regulation of alpha-beta T cell differentiation
response to cadmium ion
lung alveolus development
Peyer's patch development
embryonic digestive tract development
negative regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive regulation of T cell receptor signaling pathway
positive regulation of T cell activation
negative regulation of penile erection
negative regulation of thymocyte apoptotic process
negative regulation of mucus secretion
response to L-arginine
IMP salvage
inhibition of non-skeletal tissue mineralization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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