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Invitrogen
C11orf85 Polyclonal Antibody
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Product Details
PA5-34721
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human LOC283129. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
C11orf85, also known as PCIF1 (phosphorylated CTD-interacting factor 1), is located on chromosome 11. This gene encodes a protein that plays a critical role in post-transcriptional modification and regulation processes. PCIF1 is involved in the methylation of mRNA, specifically adding a methyl group to the 2'-O position of the first nucleotide adjacent to the cap structure of mRNA. This cap-specific mRNA (nucleoside-2'-O-)-methyltransferase activity is crucial for mRNA stability, translation, and the regulation of gene expression. The PCIF1 protein also has interactions with RNA polymerase II and is involved in the maturation and processing of nascent mRNA transcripts. Studies have shown that the disruption of PCIF1 function can lead to altered RNA metabolism and has potential implications in a variety of cellular processes, including immune responses and ferroptosis resistance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK085; LOC283129; Membrane-anchored junction protein; unnamed protein product
Gene Aliases: C11orf85; MAJIN
UniProt ID: (Human) Q3KP22
Entrez Gene ID: (Human) 283129
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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