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Invitrogen
Phospho-NMDAR2C (Ser1096) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-NMDAR2C (Ser1096) Antibody (PA5-35402) in WB
Western blot of NMDAR2C in mouse brain lysate showing specific immunolabeling of a band at ~140 kDa corresponding to Phospho-NMDAR2C (Ser1096) polyclonal antibody (Product # PA5-35402) in the first lane (-). Phosphospecificity is shown in the second lane (+) where immunolabeling is blocked by pre-adsorption of the phosphopeptide used as the antigen, but not by the corresponding non-phosphopeptide (not shown... View More
Product Details
PA5-35402
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1096 of rat GRIN2C conjugated to KLH
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 50% glycerol, 0.1mg/mL BSA, 0.15M NaCl
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine, human and non-human primate based on 100% sequence homology.
This antibody contains enough material to conduct 10 mini-Western blots.
Target Information
The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GluN2C; GluRepsilon3; Glutamate [NMDA] receptor subunit epsilon-3; glutamate receptor; Glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, NMDA2C; N-methyl D-aspartate receptor subtype 2C; NMDA glutamate receptor; NMDAR2C; NR2
Gene Aliases: GluN2C; Grin2c; NMDAR2C; NR2C
UniProt ID: (Mouse) Q01098, (Rat) Q00961
Entrez Gene ID: (Mouse) 14813, (Rat) 24411
startle response
transport
ion transport
protein localization
response to wounding
directional locomotion
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
synaptic transmission, glutamatergic
negative regulation of protein catabolic process
regulation of membrane potential
neuromuscular process controlling balance
excitatory postsynaptic potential
cation transmembrane transport
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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