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Invitrogen
PDDC1 Polyclonal Antibody
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FIGURE: 1 / 1
PDDC1 Antibody (PA5-35945) in IHC (P)
PDDC1 Polyclonal Antibody detects PDDC1 protein at cytosol on rat hind brain by immunohistochemical analysis. Sample: Paraffin-embedded rat hind brain. PDDC1 Polyclonal Antibody (Product # PA5-35945) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-35945
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PDDC1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Human (93%), Mouse (86%), Rat (86%), Bovine (85%).
Target Information
The PDDC1 (Parkinson Disease 7 Domain Containing 1) gene encodes a protein that is part of the DJ-1 protein family, known for its role in protecting cells against oxidative stress and neurodegenerative conditions. PDDC1 has been implicated in various cellular processes such as transcription regulation, response to oxidative damage, and cellular homeostasis. It is located on human chromosome 12 and is expressed in several tissues, including the brain. Although its exact function remains to be fully elucidated, PDDC1 shares homology with Parkinson's disease-associated protein DJ-1, suggesting a potential role in neuroprotection. Research indicates that PDDC1 might be involved in neural development and survival, and its dysregulation could contribute to diseases involving oxidative stress and neurodegeneration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ferry endosomal RAB5 effector complex subunit 5; Fy-5; glutamine amidotransferase like class 1 domain containing 1; Glutamine amidotransferase-like class 1 domain-containing protein 1; Parkinson disease 7 domain containing 1; Parkinson disease 7 domain-containing protein 1; unnamed protein product
Gene Aliases: FERRY5; Fy-5; GATD1; PDDC1; RGD1304836
UniProt ID: (Human) Q8NB37
Entrez Gene ID: (Human) 347862, (Rat) 309110
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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