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Invitrogen
Phospho-Histone H2A (Ser129) Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-40149
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around phosphorylation site of serine 129(K-A-Q-S(p)-K) derived from Human Histone H2A.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
whole serum, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetyl-Histone H2; H2A 615 antibody; H2A GL101 antibody; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member R; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1 antibody; H2A/d; H2a/x; h2ad; H2ae; H2AFX; H2AFZ; h2ai; H2ak; H2AK5ac; H2AX histone; H2AZ histone; H2B histone family, member U, (testis-specific); HIS; HIST1H2AE antibody; HIST1H3D; HIST3H2A; histone (H2A.Z); histone 1, H2aa; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ah; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone 2, H2ai; histone 5 protein 2ax; histone cluster 1 H2A family member a; histone cluster 1 H2A family member b; histone cluster 1 H2A family member d; histone cluster 1 H2A family member e; histone cluster 1 H2A family member g; histone cluster 1 H2A family member h; histone cluster 1 H2A family member i; histone cluster 1 H2A family member j; histone cluster 1 H2B family member a; histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2ba; histone H2A type 1; Histone H2A type 1-B; Histone H2A type 1-E; Histone H2A type 1-G; histone H2A type 1-H; Histone H2A type 1-I; histone H2A, testis; histone H2A.3; histone H2A.x; histone H2A/a; histone H2A/g; histone H2A/m; histone H2A/p; histone H2A/ptl; histone H2A/r; histone H2A/s; histone H2AD; histone H2AE; histone H2B, testis; MGC74460 antibody; testis-specific histone 2a; testis-specific histone 2b; testis-specific histone H2B; unnamed protein product
Gene Aliases: 1190022L06; bA317E16.2; bA317E16.3; dJ160A22.4; dJ86C11.1; gammaH2ax; H2a-291A; H2a-53; H2A.1; H2A.1b; H2A.2; H2A.3; H2A.X; H2A.Z; H2A.Z-1; H2A.Z1; H2A/a; H2A/c; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2A/X; H2A/z; H2AA; H2AFA; H2AFALii; H2AFC; H2AFE; H2AFG; H2AFM; H2AFP; H2AFR; H2AFX; H2AFZ; H2AG; H2AH; H2AZ; H2BFU; HIST1H2AA; HIST1H2AB; HIST1H2AD; HIST1H2AE; HIST1H2AG; HIST1H2AH; HIST1H2AI; HIST1H2AJ; HIST1H2BA; Hist5-2ax; HISTH2AA; histone; hTSH2B; pH2A/f; RGD1566119; STBP; TH2A; TH2B; TSH2B; TSH2B.1
UniProt ID: (Human) Q96QV6, (Human) P0C0S8, (Human) Q96KK5, (Human) Q99878, (Human) P04908, (Human) P20671, (Human) P16104, (Human) P0C0S5, (Human) Q96A08, (Rat) Q00728, (Mouse) C0HKE5, (Mouse) Q8CGP6, (Mouse) C0HKE6, (Mouse) C0HKE1, (Mouse) C0HKE3, (Mouse) C0HKE4, (Mouse) P27661, (Mouse) P0C0S6, (Rat) P0C0S7, (Rat) Q00729
Entrez Gene ID: (Human) 221613, (Human) 8969, (Human) 85235, (Human) 8329, (Human) 8331, (Human) 8335, (Human) 3013, (Human) 3012, (Human) 3014, (Human) 3015, (Human) 255626, (Rat) 24828, (Mouse) 319167, (Mouse) 319168, (Rat) 680322, (Mouse) 319191, (Mouse) 319172, (Mouse) 319165, (Mouse) 319166, (Rat) 500987, (Mouse) 15270, (Mouse) 51788, (Rat) 58940, (Rat) 24829
DNA binding
structural constituent of chromatin
protein heterodimerization activity
protein binding
enzyme binding
damaged DNA binding
histone binding
chromatin-protein adaptor activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
chromatin DNA binding
nucleosomal DNA binding
DNA damage checkpoint
double-strand break repair via homologous recombination
DNA repair
chromatin organization
nucleosome disassembly
cellular response to DNA damage stimulus
spermatogenesis
negative regulation of cell proliferation
cerebral cortex development
heterochromatin assembly
UV-damage excision repair
cellular response to gamma radiation
cellular senescence
protein localization to site of double-strand break
protein localization to CENP-A containing chromatin
positive regulation of transcription from RNA polymerase II promoter
cellular response to estradiol stimulus
cellular response to insulin stimulus
nucleosome assembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
double-strand break repair
response to ionizing radiation
positive regulation of DNA repair
protein K63-linked ubiquitination
positive regulation of double-strand break repair via homologous recombination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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