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Invitrogen
Phospho-delta Catenin (Tyr228) Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-40286
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human p120 around the phosphorylation site of Y228.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Armadillo protein; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin src; hp120ctn-1A; hp120ctn-1AB; hp120ctn-1ABC; hp120ctn-1AC; hp120ctn-1B; hp120ctn-2A; hp120ctn-2AB; hp120ctn-2ABC; hp120ctn-2AC; hp120ctn-2B; hp120ctn-3A; hp120ctn-3AB; hp120ctn-3ABC; hp120ctn-3AC; hp120ctn-3B; hp120ctn-4A; hp120ctn-4AB; hp120ctn-4ABC; hp120ctn-4AC; hp120ctn-4B; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); unnamed protein product
Gene Aliases: BCDS2; CAS; Catns; CTNND; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN
UniProt ID: (Human) O60716, (Mouse) P30999
Entrez Gene ID: (Human) 1500, (Rat) 311163, (Mouse) 12388
receptor binding
protein binding
phosphatase inhibitor activity
phosphatase binding
cadherin binding
protein binding involved in cell-cell adhesion
protein sequestering activity
beta-catenin binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
cell adhesion molecule binding
protein tyrosine kinase binding
negative regulation of transcription from RNA polymerase II promoter
cell migration involved in sprouting angiogenesis
negative regulation of glucose transport
cell-cell adhesion mediated by cadherin
protein stabilization
cell-cell adhesion
regulation of postsynaptic membrane neurotransmitter receptor levels
positive regulation of protein localization to cell-cell junction
negative regulation of intracellular signal transduction
negative regulation of blood vessel branching
morphogenesis of a polarized epithelium
kidney development
cell adhesion
salivary gland morphogenesis
positive regulation of protein processing
epithelial cell differentiation involved in salivary gland development
glomerulus morphogenesis
positive regulation of peptidyl-tyrosine autophosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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