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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptide sequence: ASEDQDIEFQ MQIPAAAFIT NFTMLIGDKV YQGEITEREK KSGDRVKEKR
Sequence homology: Cow: 79%; Dog: 79%; Guinea Pig: 79%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 93%
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686F0145; inter-alpha (globulin) inhibitor H5; inter-alpha-trypsin inhibitor heavy chain family member 5; ITI heavy chain H5; MGC10848; unnamed protein product
Gene Aliases: ITI-HC5; PP14776
UniProt ID: (Human) Q86UX2
Entrez Gene ID: (Human) 80760
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