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Invitrogen
betacellulin Polyclonal Antibody
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FIGURE: 1 / 2
betacellulin Antibody (PA5-47044) in Neu
Neutralization of betacellulin in Balb/3T3 mouse embryonic fibroblast cell line. Samples were incubated in betacellulin polyclonal antibody (Product # PA5-47044). Recombinant Mouse Betacellulin/BTC stimulates proliferation in the Balb/3T3 mouse embryonic fibroblast cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse Betacellulin/BTC (2 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse Betacellulin/BTC Antigen Affinity-purified Polyclonal Antibody. The ND50 is typi... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-47044
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant mouse Betacellulin/BTC Asp32-Gln118
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL once reconstituted
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human BTC is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000160600; OTTHUMP00000219057; probetacellulin; unnamed protein product
Gene Aliases: Bcn
UniProt ID: (Mouse) Q05928
Entrez Gene ID: (Mouse) 12223
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
positive regulation of urine volume
ERBB2-EGFR signaling pathway
ERBB4-ERBB4 signaling pathway
negative regulation of apoptotic process
positive regulation of cell differentiation
positive regulation of mitotic nuclear division
positive regulation of fibroblast proliferation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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