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Invitrogen
HIST1H2BN Polyclonal Antibody
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FIGURE: 1 / 4
HIST1H2BN Antibody (PA5-48515) in IHC (P)
Immunohistochemistry analysis of HIST1H2BN in formalin fixed and paraffin embedded human lung tissue. Samples were incubated with HIST1H2BN polyclonal antibody (Product # PA5-48515) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-48515
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BN.
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
196 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with mouse and bovine based on sequence homology.
Target Information
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H2B histone family, member D; H2B/d; histone 1, H2bn; histone cluster 1 H2B family member n; histone cluster 1, H2bn; Histone H2B type 1-N; Histone H2B.d; Histone H2Bd; unnamed protein product
Gene Aliases: H2B/d; H2BC15; H2BFD; HIST1H2BN
UniProt ID: (Human) Q99877
Entrez Gene ID: (Human) 8341
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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