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FIGURE: 1 / 6
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
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Protein Aliases: EHD2; FLJ96617; PAST homolog 2; putative eps protein; similar to EHD1; unnamed protein product
Gene Aliases: C130052H20Rik; MGEPS; PAST2
UniProt ID: (Human) Q9NZN4, (Mouse) Q8BH64, (Rat) Q4V8H8
Entrez Gene ID: (Human) 30846, (Mouse) 259300, (Rat) 361512
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