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Invitrogen
Arp3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-49965
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from C-terminal of human ACTR3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total Arp3 protein.
Target Information
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-like protein 3; ARP3 actin related protein 3 homolog; ARP3 actin-related protein 3 homolog; one of seven subunits of the Arp2/3 protein complex; unnamed protein product
Gene Aliases: 1200003A09Rik; ARP3
UniProt ID: (Human) P61158, (Mouse) Q99JY9
Entrez Gene ID: (Human) 10096, (Mouse) 74117
positive regulation of lamellipodium assembly
Arp2/3 complex-mediated actin nucleation
positive regulation of transcription from RNA polymerase II promoter
cilium morphogenesis
actin polymerization-dependent cell motility
establishment or maintenance of cell polarity
spermatogenesis
asymmetric cell division
positive regulation of fibroblast migration
meiotic chromosome movement towards spindle pole
negative regulation of axon extension
positive regulation of actin filament polymerization
response to estradiol
regulation of actin cytoskeleton organization
meiotic cytokinesis
cellular response to trichostatin A
regulation of myosin II filament organization
positive regulation of neuron differentiation
astrocyte differentiation
positive regulation of astrocyte differentiation
positive regulation of dendrite morphogenesis
meiotic cell cycle
positive regulation of filopodium assembly
spindle localization
positive regulation of synapse assembly
positive regulation of dendritic spine morphogenesis
Sertoli cell barrier remodeling
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to epidermal growth factor stimulus
response to heparin
cellular response to transforming growth factor beta stimulus
positive regulation of protein targeting to membrane
postsynaptic actin cytoskeleton organization
postsynapse organization
positive regulation of protein localization to plasma membrane
negative regulation of bleb assembly
cellular response to pyrimidine ribonucleotide
cellular response to triterpenoid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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