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Invitrogen
VPS51 Polyclonal Antibody
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Product Details
PA5-67596
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human VPS51.
Conjugate
Form
Liquid
Concentration
1.6 mg/mL
Amount
160 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse samples.
Target Information
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Another new gene 2 protein; C11orf2; Protein fat-free homolog; vacuolar protein sorting 51 homolog; Vacuolar protein sorting-associated protein 51 homolog; VPS51, GARP complex subunit
Gene Aliases: 1110014N23Rik; 3110057M17Rik; AI837850; ANG2; ANG3; C11orf2; C11orf3; FFR; PCH13; PP5382; VPS51
UniProt ID: (Human) Q9UID3, (Mouse) Q3UVL4
Entrez Gene ID: (Human) 738, (Mouse) 68505
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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