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Invitrogen
LPHN3 Polyclonal Antibody
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Product Details
PA5-67880
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human LPHN3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor L3; Calcium-independent alpha-latrotoxin receptor 3; calcium-independent alpha-latrotoxin receptor homolog 3; CIRL-3; latrophilin 3; latrophilin homolog 3 (cow); Latrophilin-3; lectomedin 3; Lectomedin-3; Lph3; unnamed protein product
Gene Aliases: 5430402I23Rik; ADGRL3; CIRL-3; CIRL3; CL3; D130075K09Rik; Gm1379; KIAA0768; LEC3; LPHN3; mKIAA0768
UniProt ID: (Human) Q9HAR2, (Mouse) Q80TS3, (Rat) Q9Z173
Entrez Gene ID: (Human) 23284, (Mouse) 319387, (Rat) 170641
neuron migration
cell adhesion
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
synapse assembly
cell-cell adhesion via plasma-membrane adhesion molecules
Rho-activating G protein-coupled receptor signaling pathway
excitatory synapse assembly
positive regulation of synapse assembly
brain development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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