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Invitrogen
SPANXC Polyclonal Antibody
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Product Details
PA5-70461
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of human SPANXC
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This target displays homology in the following species: Human: 100%
Target Information
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer-testis-associated protein CTp11; cancer/testis antigen 11.3; cancer/testis antigen family 11, member 3; cancer/testis-associated protein of 11 kD; nuclear-associated protein SPAN-Xc; Nuclear-associated protein SPAN-Xe; SPAN-Xc protein; Sperm protein associated with the nucleus on the X chromosome E; sperm protein associated with the nucleus, X chromosome, family member C
Gene Aliases: CT11.3; CTp11; SPANX-C; SPANX-E; SPANXE
UniProt ID: (Human) Q9NY87
Entrez Gene ID: (Human) 64663
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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