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14-3-3 eta Polyclonal Antibody
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FIGURE: 1 / 4
14-3-3 eta Antibody (PA5-75298) in IHC (P)
Immunohistochemistry analysis of 14-3-3 eta in paraffin-embedded human breast carcinoma tissue (cytoplasmic and nucleus staining) and negative control (right, with PBS only). Samples were incubated with 14-3-3 eta polyclonal antibody (Product # PA5-75298) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-75298
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 50-100 of Human 14-3-3 eta.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 eta; 14-3-3 protein eta-subtype; 14-3-3n; 1433F; AS1; brain-specific tyrosine and tryptophan hydroxylase activator; similar to Homo sapiens DNA for 14-3-3 protein eta chain, exon 2 with GenBank Accession Number D78577.1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; unnamed protein product; YWHA114-3-3 eta; YWHAH
Gene Aliases: 14-3-3e; YWHA1
UniProt ID: (Human) Q04917, (Mouse) P68510, (Rat) P68511
Entrez Gene ID: (Human) 7533, (Mouse) 22629, (Rat) 25576
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
cytoskeleton organization
regulation of mitotic nuclear division
signal transduction
protein localization
glucocorticoid receptor signaling pathway
negative regulation of apoptotic process
establishment of protein localization
positive regulation of transcription, DNA-templated
negative regulation of dendrite morphogenesis
membrane depolarization during action potential
presynaptic modulation of chemical synaptic transmission
substantia nigra development
regulation of neuron differentiation
regulation of synaptic plasticity
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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