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Invitrogen
Oxytocin Polyclonal Antibody
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Product Details
PA5-75431
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 11-60 of Human Oxytocin.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: neurophysin 1; neurophysin I; OT-NPI; oxcytocin; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; Oxytocin-neurophysin 1; oxytocin-neurophysin I, preproprotein; oxytocin/neurophysin (Oxt) gene, complete gene, complete cds
Gene Aliases: OT; OT-NPI; OXT; OXT-NPI; Oxy
UniProt ID: (Human) P01178, (Mouse) P35454, (Rat) P01179
Entrez Gene ID: (Human) 5020, (Mouse) 18429, (Rat) 25504
response to amphetamine
regulation of heart rate
maternal aggressive behavior
signal transduction
positive regulation of cytosolic calcium ion concentration
heart development
female pregnancy
memory
grooming behavior
response to sucrose
positive regulation of norepinephrine secretion
response to activity
response to food
positive regulation of prostaglandin secretion
response to estradiol
response to retinoic acid
response to progesterone
response to genistein
response to prostaglandin E
social behavior
intracellular signal transduction
negative regulation of urine volume
response to cocaine
maternal behavior
sperm ejaculation
eating behavior
drinking behavior
response to peptide hormone
response to ether
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of ossification
positive regulation of female receptivity
response to steroid hormone
positive regulation of synaptic transmission
response to glucocorticoid
response to cAMP
response to electrical stimulus
positive regulation of synapse assembly
male mating behavior
positive regulation of penile erection
positive regulation of hindgut contraction
positive regulation of uterine smooth muscle contraction
positive regulation of cold-induced thermogenesis
response to organic cyclic compound
sleep
positive regulation of renal sodium excretion
regulation of digestive system process
regulation of sensory perception of pain
negative regulation of gastric acid secretion
parturition
lactation
response to mechanical stimulus
hyperosmotic salinity response
response to external biotic stimulus
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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