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Invitrogen
IL1RA Polyclonal Antibody
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FIGURE: 1 / 3
IL1RA Antibody (PA5-79488) in IHC (P)
Immunohistochemistry (Paraffin) analysis of IL1RA in paraffin-embedded section of human esophageal squamous carcinoma tissue using IL1RA Polyclonal Antibody (Product # PA5-79488). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL di... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79488
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human IL1RA recombinant protein (Position: R26-E177).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human RT4 whole cell, human Hacat whole cell. IHC: human esophageal squamous carcinoma tissue. Flow: U937 cell.
Target Information
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD121A; D2S1473; IL 1 receptor antagonist; il-1 receptor; il-1r; IL-1R-alpha; IL1 inhibitor; il1 receptor; IL1 receptor antagonist; IL1-RA; IL1R; IL1RN; IL1RN (IL1F3); interleukin-1 receptor; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); MGC10430; P80; type II interleukin-1 receptor antagonist; unnamed protein product
Gene Aliases: CRMO2; DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
UniProt ID: (Human) P18510
Entrez Gene ID: (Human) 3557
negative regulation of cytokine-mediated signaling pathway
acute-phase response
inflammatory response
immune response
signal transduction
negative regulation of heterotypic cell-cell adhesion
negative regulation of inflammatory response
response to glucocorticoid
negative regulation of interleukin-1-mediated signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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