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FIGURE: 1 / 1
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat brain tissue, rat ovary tissue, mouse brain tissue, mouse testicular tissue, mouse ovary tissue, mouse NIH/3T3 whole cell, human placenta tissue, human HEK293 whole cell, monkey COS-7 whole cell, human PC-3 whole cell, human 22RV1 whole cell, human K562 whole cell.
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cyclic dinucleotide:anion antiporter SLC19A1; folate transporter 1; Folate:anion antiporter SLC19A1; FOLT; hSLC19A1; IFC-1; Intestinal folate carrier 1; intestinal folate carrier protein; Methotrexate carrier 1; methotrexate carrier 2; methotrexate carrier 5; methotrexate carrier 6; MTX-1; Placental folate transporter; Plasma membrane folate antiporter SLC19A1; Reduced folate carrier 1; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; RFC; RFC-1; RFC1; RFT-1; solute carrier family 19 (sodium/hydrogen exchanger), member 1; Solute carrier family 19 member 1; solute carrier family 19, member 1
Gene Aliases: AI323572; FLOT1; MTX1; RFC; RFC-1; RFC1; SLC19A1
UniProt ID: (Mouse) P41438, (Rat) Q62866
Entrez Gene ID: (Mouse) 20509, (Rat) 29723
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