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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Purity is > 95% by SDS-PAGE.
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re imported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HDP; HDP-1; Helix-destabilizing protein; Heterogeneous nuclear ribonucleoprotein A1; hnRNP A1; hnRNP A1-like 3; hnRNP core protein A1; hnRNP I; HNRNP-I; HNRNPI; HNRPA1MGC102835; HNRPI; MGC102835; pPTB; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4; RP11-78J21.1; Single-strand RNA-binding protein; Single-strand-binding protein; Topoisomerase-inhibitor suppressed
Gene Aliases: Fli-2; Hdp; HDP-1; hnRNP A1; hnrnp-A1; HNRNPA1; HNRPA1; Tis
UniProt ID: (Mouse) P49312, (Rat) P04256
Entrez Gene ID: (Mouse) 15382, (Rat) 29578
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