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Invitrogen
RAB34 Polyclonal Antibody
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FIGURE: 1 / 1
RAB34 Antibody (PA5-87817) in WB
Western blot analysis of RAB34 in extracts of various cell lines. Samples were incubated with RAB34 Polyclonal antibody (Product # PA5-87817) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-87817
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human RAB34 (NP_1141404)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.52 mg/mL
Amount
152 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MNILAPVRRD RVLAELPQCL RKEAALHGHK DFHPRVTCAC QEHRTGTVGF KISKVIVVGD LSVGKTCLIN RFCKDTFDKN YKATIGVDFE MERFEVLGIP FSLQLWDTAG QERFKCIAST YYRGAQAIII VFNLNDVASL EHTKQWLADA LKENDPSSVL LFLVGSKKDL STPAQYALME KDALQVAQEM KAEYWAVSSL TGENVREFFF RVAALTFEAN VLAELEKSGA RRIGDVVRIN SDDSNLYLTA SKKKPTCCP; Positive Samples: Mouse lung, Mouse brain, Mouse kidney, Mouse testis; Cellular Location: Nucleus, nucleolus
Target Information
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: low-molecular-weight GTP-binding protein; nine amino-acid residue-repeats; Rab family GTPase; rab-39; RAB34, member of RAS oncogene family; ras-related homolog; ras-related protein Rab-39; Ras-related protein RAB34; ras-related protein Rah; unnamed protein product
Gene Aliases: NARR; OFD20; RAB39; RAH; Rah1
UniProt ID: (Human) P0DI83, (Mouse) Q64008, (Rat) Q5U1Y1
Entrez Gene ID: (Human) 83871, (Mouse) 19376, (Rat) 360571
endocytosis
lysosomal transport
antigen processing and presentation
lysosome localization
Golgi to plasma membrane protein transport
positive regulation of smoothened signaling pathway
positive regulation of protein secretion
cilium morphogenesis
cytosolic ciliogenesis
cellular response to glucose stimulus
protein localization to plasma membrane
phagosome maturation
phagosome-lysosome fusion
positive regulation of defense response to bacterium
positive regulation of protein localization to phagocytic vesicle
macropinocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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