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FZD6 Polyclonal Antibody
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FIGURE: 1 / 1
FZD6 Antibody (PA5-87953) in WB
Western blot analysis of FZD6 in extracts of various cell line. Samples were incubated with FZD6 Polyclonal antibody (Product # PA5-87953) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-87953
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.13 mg/mL
Amount
213 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HSLFTCEPIT VPRCMKMAYN MTFFPNLMGH YDQSIAAVEM EHFLPLANLE CSPNIETFLC KAFVPTCIEQ IHVVPPCRKL CEKVYSDCKK LIDTFGIRWP EELECDRLQY CDETVPVTFD PHTEFLGPQK KTEQVQRDIG FWCPRHLKTS GGQGYKFLGI DQCAPPCPNM YFKSDELEFA KSF; Positive Samples: mouse kidney, rat kidney; Cellular Location: Apical cell membrane, Cell membrane, Cell surface, Cytoplasmic vesicle membrane, Membrane, Multi-pass membrane protein
Target Information
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: frizzled family receptor 6; frizzled homolog 6; Frizzled6; fz-6; FZD-6; mFz6; unnamed protein product
Gene Aliases: Fz6; rst
UniProt ID: (Mouse) Q61089
Entrez Gene ID: (Rat) 282581, (Mouse) 14368
negative regulation of transcription from RNA polymerase II promoter
establishment of planar polarity
neural tube closure
hair follicle development
cell surface receptor signaling pathway
biological_process
platelet activation
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
embryonic nail plate morphogenesis
inner ear morphogenesis
establishment of body hair planar orientation
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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