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Invitrogen

NME1/NME2 Polyclonal Antibody

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View all (7) NME1/NME2 antibodies

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Product Details

PA5-89022

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein (or fragment)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.74 mg/mL

Amount

74 µg

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2805305

Product Specific Information

Immunogen sequence: MANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRTMANLE RTFIAIKPDG VQRGLVGEII KRFEQKGFRL VAMKFLRASE EHLKQHYIDL KDRPFFPGLV KYMNSGPVVA MVWEGLNVVK TGRVMLGETN PADSKPGTIR GDFCIQVGRN IIHGSDSVKS AEKEISLWFK PEELVDYKSC AHDWVYE; Positive Samples: U-87MG, OVCAR-3, Mouse kidney, Rat kidney, Rat liver; Cellular Location: Cell projection, Cytoplasm, Nucleus, lamellipodium, ruffle

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: c-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein; epididymis secretory sperm binding protein Li 155an; expressed in non-metastatic cells 1, protein; expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase); expressed in non-metastatic cells 2; expressed in non-metastatic cells 2 protein; farnesyl diphosphate kinase NME1; granzyme A-activated DNase; HEL-S-155an; histidine protein kinase NDK; histidine protein kinase NDKB; histidine protein kinase NME1; metastasis inhibition factor NM23; NDK A; NDK B; NDP kinase A; NDP kinase alpha; NDP kinase B; NDP kinase beta; nm23-H2S product (putative NDP kinase); putative; NM23H1; NME1; NME2; non-metastatic cells 1, protein (NM23A) expressed in; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; non-specific serine/threonine protein kinase NME1; nucleoside diphoshate kinase 1; nucleoside diphoshate kinase 2; nucleoside diphosphate kinases 2; nucleoside-diphosphate kinase 1; nucleoside-diphosphate kinase 2; nucleotide diphosphate kinase; nucleotide diphosphate kinase B; nucloside diphosphate kinase; P18; putative 3'-5'-DNA exonuclease NDK1; putative granzyme A-activated DNA endonuclease; tumor metastatic process-associated protein; tumor metastatic process-associated protein NM23; unnamed protein product

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Gene Aliases: AWD; GAAD; NB; NBS; NDK1; NDK2; NDKA; NDKB; NDPK A; NDPK B; NDPK-A; NDPK-B; NDPK2; NDPKA; NDPKB; NM23; nm23-2; NM23-H1; NM23-H2; NM23-M1; nm23-M2; NM23A; NM23B; p18-12d; PUF

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UniProt ID: (Human) P15531, (Human) P22392, (Mouse) P15532, (Rat) Q05982, (Mouse) Q01768, (Rat) P19804

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Entrez Gene ID: (Human) 4830, (Human) 4831, (Mouse) 18102, (Rat) 191575, (Mouse) 18103, (Rat) 83782

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Function(s)
magnesium ion binding DNA binding RNA binding endodeoxyribonuclease activity deoxyribonuclease activity nucleoside diphosphate kinase activity protein histidine kinase activity protein serine/threonine kinase activity protein binding 3'-5'-exodeoxyribonuclease activity kinase activity phosphotransferase activity, phosphate group as acceptor GDP binding identical protein binding ribosomal small subunit binding ADP binding farnesyl diphosphate kinase activity protein serine kinase activity coenzyme A binding succinyl-CoA binding acetyl-CoA binding bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding nuclease activity G-quadruplex DNA binding RNA polymerase II regulatory region sequence-specific DNA binding single-stranded DNA binding intermediate filament binding enzyme binding protein kinase binding gamma-tubulin binding fatty acid binding heterocyclic compound binding
Process(es)
GTP biosynthetic process UTP biosynthetic process dTMP biosynthetic process CTP biosynthetic process integrin-mediated signaling pathway nucleoside triphosphate biosynthetic process regulation of fatty acid biosynthetic process positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter negative regulation of myeloid leukocyte differentiation DNA catabolic process apoptotic DNA fragmentation isoprenoid metabolic process nucleoside phosphate metabolic process lactation nucleoside diphosphate metabolic process negative regulation of gene expression positive regulation of neuron projection development mammary gland development protein hexamerization ITP biosynthetic process acetyl-CoA catabolic process positive regulation of epithelial cell proliferation purine-containing compound metabolic process response to xenobiotic stimulus response to amine hippocampus development response to testosterone response to cAMP cellular response to glucose stimulus cellular response to fatty acid cellular response to xenobiotic stimulus cell adhesion nucleotide biosynthetic process negative regulation of apoptotic process positive regulation of keratinocyte differentiation regulation of epidermis development positive regulation of DNA-templated transcription, initiation adenylate cyclase-activating G-protein coupled receptor signaling pathway cellular response to oxidative stress protein autophosphorylation response to growth hormone base-excision repair negative regulation of cell proliferation granzyme-mediated apoptotic signaling pathway regulation of apoptotic process
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