Search
Invitrogen
Cystatin C Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation'] || 'Additional Information'}}:
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
FIGURE: 1 / 1
Cystatin C Antibody (PA5-89137) in WB
Western blot analysis of Cystatin C in extracts of various cell lines. Samples were incubated with Cystatin C Polyclonal antibody (Product # PA5-89137) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 5s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-89137
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human Cystatin C (NP_0000901)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.05 mg/mL
Amount
205 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SSPGKPPRLV GGPMDASVEE EGVRRALDFA VGEYNKASND MYHSRALQVV RARKQIVAGV NYFLDVELGR TTCTKTQPNL DNCPFHDQPH LKRKAFCSFQ IYAVPWQGTM TLSKSTCQDA; Positive Samples: U-251MG, SKOV3, A-549, Mouse brain
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AD8; bA218C14.4 (cystatin C); CST3; cystatin 3; Cystatin C (cysteine proteinase inhibitor); cystatin-3; Cystatin3; CystatinC; epididymis secretory protein Li 2; gamma-trace; MGC117328; neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; post-gamma-globulin; RP23-250M11.9; unnamed protein product
Gene Aliases: ADLDWA; ARMD11; CYSC; HEL-S-2
UniProt ID: (Human) P01034, (Mouse) P21460, (Rat) P14841
Entrez Gene ID: (Human) 1471, (Mouse) 13010, (Rat) 25307
eye development
response to hypoxia
defense response
salivary gland development
embryo implantation
positive regulation of cell proliferation
male gonad development
response to xenobiotic stimulus
response to toxic substance
response to carbohydrate
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
response to nutrient levels
response to estradiol
regulation of tissue remodeling
cellular response to oxidative stress
positive regulation of DNA replication
negative regulation of proteolysis
response to axon injury
Sertoli cell development
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
cellular response to hydrogen peroxide
fibril organization
immune response
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support