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Invitrogen
UCN2 Polyclonal Antibody
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FIGURE: 1 / 1
UCN2 Antibody (PA5-93012) in WB
Western blot analysis of UCN2 in extracts of rat skin. Samples were incubated with UCN2 Polyclonal antibody (Product # PA5-93012) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-93012
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.79 mg/mL
Amount
179 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Rat skin
Target Information
UCN2 (Urocortin 2) is a Protein Coding gene. Diseases associated with UCN2 include Body Mass Index Quantitative Trait Locus 11. Among its related pathways are Signaling by GPCR and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and G protein-coupled receptor binding. An important paralog of this gene is UCN3. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ucn II; urocortin 3; Urocortin II; Urocortin-2
Gene Aliases: Ucn II; Ucn-2; ucn-II; Ucn2; Ucn3
UniProt ID: (Mouse) Q99ML8
Entrez Gene ID: (Mouse) 171530, (Rat) 170896
cAMP biosynthetic process
response to stress
adenylate cyclase-activating G-protein coupled receptor signaling pathway
digestion
cell proliferation
negative regulation of gene expression
cellular response to nutrient levels
negative regulation of luteinizing hormone secretion
negative regulation of follicle-stimulating hormone secretion
response to immobilization stress
tissue regeneration
cellular response to glucocorticoid stimulus
cellular response to hypoxia
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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