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Invitrogen
PLA2G2D Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-93147
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.29 mg/mL
Amount
129 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GILNLNKMVK QVTGKMPILS YWPYGCHCGL GGRGQPKDAT DWCCQTHDCC YDHLKTQGCS IYKDYYRYNF SQGNIHCSDK GSWCEQQLCA CDKEVAFCLK RNLDTYQKRL RFYWRPHCRG QTPGC; Positive Samples: HL-60, THP-1
Target Information
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GIID sPLA2; group IID sPLA2; phosphatidylcholine 2-acylhydrolase 2D; PLA2IID; secretory phospholipase A2s; secretory-type PLA, stroma-associated homolog; SPLASH; unnamed protein product
Gene Aliases: GIID; GIID sPLA2; mGIID; PLA2IID; sPLA2-IID; sPLA2S; SPLASH
UniProt ID: (Human) Q9UNK4, (Mouse) Q9WVF6
Entrez Gene ID: (Human) 26279, (Mouse) 18782, (Rat) 298579
regulation of acute inflammatory response to antigenic stimulus
phospholipid metabolic process
inflammatory response
lipid catabolic process
negative regulation of T cell proliferation
phosphatidylethanolamine metabolic process
phosphatidylcholine metabolic process
phosphatidylglycerol metabolic process
arachidonic acid secretion
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
lipid metabolic process
negative regulation of T cell activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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