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Invitrogen
Serum Amyloid P Polyclonal Antibody
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FIGURE: 1 / 4
Serum Amyloid P Antibody (PA5-96028) in IHC (P)
Immunohistochemistry analysis of Serum Amyloid P in paraffin-embedded mouse liver. Samples were incubated with Serum Amyloid P Polyclonal antibody (Product # PA5-96028) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-96028
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-223 of human APCS (NP_0016301)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.46 mg/mL
Amount
246 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: 293T
Immunogen sequence: MNKPLLWISV LTSLLEAFAH TDLSGKVFVF PRESVTDHVN LITPLEKPLQ NFTLCFRAYS DLSRAYSLFS YNTQGRDNEL LVYKERVGEY SLYIGRHKVT SKVIEKFPAP VHICVSWESS SGIAEFWING TPLVKKGLRQ GYFVEAQPKI VLGQEQDSYG GKFDRSQSFV GEIGDLYMWD SVLPPENILS AYQGTPLPAN ILDWQALNYE IRGYVIIKPL VWV
Target Information
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 9.5S alpha-1-glycoprotein; amyloid P component precursor; APCS; APCS amyloid P-component serum protein; epididymis secretory sperm binding protein Li 92n; MGC88159; Pentaxin related; pentaxin-related; Pentraxin 2; pentraxin-2; pentraxin-related; pre-serum amyloid P component; PTX 2; SAMP; unnamed protein product
Gene Aliases: HEL-S-92n; PTX2; SAP
UniProt ID: (Human) P02743, (Rat) P23680, (Mouse) P12246
Entrez Gene ID: (Human) 325, (Rat) 29339, (Mouse) 20219
negative regulation of acute inflammatory response
protein folding
acute-phase response
negative regulation by host of viral glycoprotein metabolic process
innate immune response
negative regulation of monocyte differentiation
negative regulation of viral entry into host cell
negative regulation of viral process
chaperone-mediated protein complex assembly
negative regulation of wound healing
negative regulation of glycoprotein metabolic process
protein-containing complex assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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