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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-96114
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic Peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.23 mg/mL
Amount
23 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HeLa, H3 protein; Cellular Location: Chromosome, Nucleus
Immunogen sequence: ARKST
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 K9; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; H3/b; H3/d; H3/f; H3/j; H3K9; H3K9me; H3Lys9me; H3Lys9me1; HIST1H3A; HIST1H3F; histone 1, H2ai; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 1, H3j; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1 H2a family member I like 1; histone cluster 1 H3 family member A; histone cluster 1 H3 family member b; histone cluster 1 H3 family member f; histone cluster 1 H3 family member h; histone cluster 1 H3 family member j; histone cluster 1, H2ai-like; histone cluster 1, H2ai-like1; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 1, H3j; histone cluster 2 H3 family member a; histone cluster 2 H3 family member c; histone cluster 2 H3C family member 2; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; Histone H3; histone H3.1; histone H3/a; histone H3/i; histone H3/j; histone H3/k; histone H3/l; histone H3/m; histone H3/o; Histone H3K9me1; methyl Histone 3; methyl Histone H3; Methyl-H3 K9; Methyl-H3 Lys9; Methyl-Histone H3 K9; Methyl-Histone H3 Lys9; Mono-methyl H3; Mono-methyl Histone H3; Mono-Methyl-Histone H3 K9; Mono-Methyl-Histone H3 Lys9; unnamed protein product
Gene Aliases: H3; H3 histone; H3-291; H3-53; H3-614; H3.2; H3.2-221; H3.2-614; H3/A; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3c1; H3c10; H3c11; H3c13; H3c14; H3c15; H3c2; H3c3; H3c4; H3c6; H3c7; H3c8; H3F1K; H3F2; H3FA; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; Hist1; Hist1h2ail; Hist1h2ail1; HIST1H3A; HIST1H3B; HIST1H3F; HIST1H3H; HIST1H3J; HIST2H3A; HIST2H3C; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1
UniProt ID: (Human) P68431, (Human) Q71DI3, (Rat) Q6LED0, (Mouse) P68433, (Mouse) P84228
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