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Invitrogen
MR1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-96909
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.95 mg/mL
Amount
95 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse skeletal muscle; Cellular Location: Cell membrane, Endoplasmic reticulum, Endoplasmic reticulum membrane, Extracellular side, Single-pass membrane protein, Single-pass type I membrane protein
Target Information
Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: class I histocompatibility antigen-like protein; histocompatibility-2 complex class 1-like sequence; major histocompatibility complex class I-related gene protein; major histocompatibility complex, class I-like sequence; MCH class I; MHC class I-like antigen MR-1; MHC class I-like sequence; MHC class I-related gene protein; MHC class I-related protein; MHC class I-related protein 1; MHC class-I related-gene protein; unnamed protein product
Gene Aliases: H2ls; HLALS
UniProt ID: (Human) Q95460, (Rat) O19477, (Mouse) Q8HWB0
Entrez Gene ID: (Human) 3140, (Rat) 25119, (Mouse) 15064
regulation of T cell mediated immunity
positive regulation of T cell mediated cytotoxicity directed against tumor cell target
immune response
antigen processing and presentation of exogenous antigen
T cell differentiation in thymus
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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