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B4GALT6 Polyclonal Antibody
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FIGURE: 1 / 1
B4GALT6 Antibody (PA5-98892) in WB
Western Blot analysis of B4GALT6 using a B4GALT6 Polyclonal antibody (Product # PA5-98892). Positive WB detected in: A549 whole cell lysate, U251 whole cell lysate. All lanes: B4GALT6 antibody at 1:1000. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 45 kDa.
Product Details
PA5-98892
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Beta-1,4-galactosyltransferase 6 protein (70-280AA)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Amount
15 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1,4-galactosyltransferase 6; Beta-1,4-GalTase 6; beta4GalT-VI; Glucosylceramide beta-1,4-galactosyltransferase; LacCer synthase; Lactosylceramide synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6; unnamed protein product
Gene Aliases: B4Gal-T6; B4GALT6; beta4Gal-T6
UniProt ID: (Human) Q9UBX8
Entrez Gene ID: (Human) 9331
lactosylceramide biosynthetic process
carbohydrate metabolic process
protein glycosylation
lipid metabolic process
sphingolipid metabolic process
glycosphingolipid biosynthetic process
ganglioside biosynthetic process via lactosylceramide
central nervous system neuron axonogenesis
central nervous system myelination
neuron maturation
glycosylation
carbohydrate derivative biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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