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Invitrogen
COX8A Polyclonal Antibody
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FIGURE: 1 / 3
COX8A Antibody (PA5-99809) in IHC (P)
Immunohistochemistry analysis of COX8A in mouse colorectal tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with COX8A polyclonal antibody (Product # PA5-99809) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99809
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human COX8A(Accession P10176), corresponding to amino acid residues M1-F51.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total COX82.
Target Information
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COX VIII-L; COX8; Cytochrome c oxidase polypeptide VIII-liver; Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit 8A (ubiquitous); Cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIA (ubiquitous); unnamed protein product
Gene Aliases: COX; COX8; COX8-2; COX8A; COX8L; MC4DN15; VIII; VIII-L
UniProt ID: (Human) P10176, (Rat) P80433, (Mouse) Q64445
Entrez Gene ID: (Human) 1351, (Rat) 171335, (Mouse) 12868
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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