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This peptide corresponds to 16 amino acid peptide from near the center of human MDA5
PEP-0458 can be used as a blocking peptide with polyclonal antibody PA5-20338.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CADM-140 autoantigen; clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; helicase with 2 CARD domains; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; murabutide down-regulated protein; RIG-I-like receptor 2; RNA helicase-DEAD box protein 116; unnamed protein product
Gene Aliases: AGS7; Hlcd; IDDM19; IMD95; MDA-5; MDA5; RLR-2; SGMRT1
UniProt ID: (Human) Q9BYX4
Entrez Gene ID: (Human) 64135
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