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Invitrogen
Human/Rat PLLP Synthetic Peptide
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Product Details
PEP-250
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Amount
50 µg
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
This peptide corresponds to amino acids C D(127) LTSLRG (S/T) RPYNQRS (141) of human and rat Plasmolipin and can be used as a blocking peptide with polyclonal antibody PA1-086.
Target Information
Plasmolipin is an 18 kDa membrane-bound proteolipid that belongs to the tetraspan (4TM) family, a rapidly growing group of myelin-associated proteins. Many of these proteins could be linked to human hereditary demyelinating neuropathies. Studies indicate that plasmolipin is a component of the cytoskeletal structure and has been localized to the apical surface of tubular epithelial cells. It has been shown that, upon addition to lipid bilayers, plasmolipin induces formation of ion channels that are both voltage-dependent and potassium-specific. Plasmolipin was originally isolated from kidney tissue. Subsequently, it has been shown to be widely expressed, not only being present in kidney, but also in the nervous system, thymus, testis, lung, and thyroid gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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