LYN is a SRC family kinase expressed predominantly in hematopoietic cells. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYNB and the slightly shorter LYNA are the two isoforms of LYN.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
AAH59394
Molecular Weight
57.4 kDa
Quantity
100 µg
Gene Alias
Lyn B
KinaseFamily
SRC Kinase Family
Recombinant
Yes
Protein Tag
His Tag
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Full Length
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 100 mM NaCl, 0.05 mM EDTA, 0.05% NP-40, 1 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.