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Thermo Scientific™

MAP2K1 (MEK1) [S218D] [S222D] Recombinant Human Protein

Catalog number:  PR3944C

Related applications:

Protein Assays and Analysis

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Description

MAP2K1 (MEK1) kinse is a dual-specific protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. This mutant has been activated by subsituting serines 218 and 222 with aspartic acid to mimic the phosphorylated state.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_002746, S218D, S222D
Kinase Group: Ser⁄Thr Kinases: STE Group
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Full Length
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 49.2 kDa
Gene Alias: MAP2K1 (MEK1) S218D S222D
KinaseFamily: STE7 Kinase Family
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.05 mM EDTA, 0.05% NP-40, 1mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.