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Thermo Scientific™

AMPK A2/B1/G1 Recombinant Human Protein

Catalog number: PR8694C
Thermo Scientific™

AMPK A2/B1/G1 Recombinant Human Protein

Catalog number: PR8694C
Catalog Number
PR8694C
Unit Size
100 µg
Price (USD)
2,655.00
Your Price:
Availability
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Unit Size
1 mg
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Catalog Number
Unit Size
10 µg
Price (USD)
1,230.00
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PR8694C100 µg
2,655.00
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Product Overview
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Additional Information
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AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as a sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to Type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diabetes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_0062243.2 I NP_006244.2 I NP_002724.1
Kinase Group
Ser⁄Thr Kinases: CAMK Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Form
Frozen
Protein Form
Full Length
Research Category
Drug Development
Species
Human
Validated Application
Kinase Assay
Molecular Weight
190.9 kDa
Quantity
100 µg
Gene Alias
AMPK A2/B1/G1
KinaseFamily
CAMKL Kinase Family
Recombinant
Yes
Protein Tag
GST Tag, His Tag

Contents & Storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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Citations & References