LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease. The G2019S mutation of LRRK2 is associated with an increase in catalytic activity.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_940980.2, G2019S
Molecular Weight
204.9 kDa
Quantity
100 µg
Gene Alias
LRRK2 G2019S
KinaseFamily
LRRK Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Catalytic, Mutant
Form
Liquid
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Polysorbate 20, 2 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.