For order quantities > 1, multiple lots may be used to fulfill the order. If you require a single lot, please email

During checkout, this product will be reported as "Out of Stock" with an estimated availability date. Often, the actual availability date will be earlier. Send inquiries regarding actual availability date to

88 more kinases now available to order! See the complete list.

EGFR (ErbB1) [T790M] [L858R] Recombinant Human Protein

Catalog number: PR8911A

 Related applications: Protein Assays and Analysis

Error loading your content!

  Catalog number
Select a plan
Unit size
Price ({{currency}}) Your price ({{currency}}) Availability Qty
{{product.sku}} {{product.sku}}
also known as {{product.formattedSku}} 
{{subscriptionDetails.selectedRatePlan.billingPeriod}} {{subscriptionDetails.selectedRatePlan.billingPeriod}} {{product.availability.message}}
Pro add-ons

Your on-site stock

›› {{supplyCenter.scName}}({{scProduct.stockOnHand}} In stock)
›› {{supplyCenter.scName}}(Out of stock)
›› {{supplyCenter.scName}}
This item is not currently available on-site. Depending on your Supply Center settings you may be able to add the item to cart above else use the Order Non-Stocked Items' tab on the Supply Center home page.
Back to top


The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The double T790M L858R mutant of EGFR displays resistance to Erlotinib (Tarceva) and sensitivity to HKI-272 and rapamycin combination therapy.
For Research Use Only. Not for use in diagnostic procedures.


Form: Frozen
Species: Human
Gene Aliases: EGFR (ErbB1) T790M L858R
Kinase Group: Tyrosine Kinases
Product Size: 100 µg
Accession Number: NP_005219.2; T790M L858R
Molecular Weight: 90.6 kDa
Research Category: Drug Development
Protein Tag or Fusion: GST Tag
Validated Application: Kinase Assay
Expression: Baculovirus
Kinase Family: EGF Receptor (ErbB) Kinase Family
Protein Form: Cytoplasmic
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Polysorbate 20, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols