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Thermo Scientific™

TGFBR2 Recombinant Human Protein

Catalog number: PR9154A
Thermo Scientific™

TGFBR2 Recombinant Human Protein

Catalog number: PR9154A
Catalog Number
PR9154A
Unit Size
100 µg
Price (USD)
1,546.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,430.00
Your Price:
Availability
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Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PR9154A100 µg
1,546.00
Your Price:
***
PV612210 µg
451.00
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PV61231 mg
6,430.00
Your Price:
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This recombinant fusion protein consists of the catalytic domain of transforming growth factor beta receptor 2 (TGFBR2) and glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase.
Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay
Expressed in insect cells
GST tagged for use with Eu-labeled GST antibody

Easily Screen for Kinase Binding
The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measurements, and makes simple the study of type III (allosteric) inhibitors.

The LanthaScreen® Eu Kinase Binding Assay is easy to optimize and run. The assay uses a simple mix-and-read format, with a single one hour incubation and no development steps. Binding of an Alexa Fluor® conjugate or “tracer’ to a tagged kinase is detected by addition of a europium-labeled anti-tag antibody, in this case anti-GST. Simultaneous binding of the tracer and antibody to the kinase results in a high degree of fluorescence resonance energy transfer (FRET), while displacement of the tracer with a kinase inhibitor results in a loss of FRET (Fig 1).

TGFBR2 for the LanthaScreen Kinase Binding Assay
Transforming Growth Factor, beta receptor 2 (TGFBR2) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It is involved in the regulation of cell proliferation. (TGFBR2 Aliases: AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII).

This insect cell-expressed recombinant fusion protein of the TGFBR2 catalytic domain and GST tag has been validated in the LanthaScreen® Eu Kinase Binding Assay with these reagents:
 Tracer 178 (Cat No. PV5593)
 Eu-labeled GST Antibody (Cat No. PV5594)

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Related Link
•  Learn more about the LanthaScreen® Eu Binding Assay.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_003233
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Form
Frozen
Protein Form
Truncated
Protein Subtype
TGFs (Transforming Growth Factors)
Research Category
Drug Development
Species
Human
Validated Application
Kinase Assay
Molecular Weight
70.3 kDa
Quantity
100 µg
Gene Alias
TGFBR2
KinaseFamily
STKR Kinase Family
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol. Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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