MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_002741.1
Gene ID (Entrez)
5599
Molecular Weight
47.6 kDa
Purity
90% by SDS-PAGE
Quantity
100 µg
Gene Alias
MAPK8 (JNK1)
KinaseFamily
MAP Kinase Family
Recombinant
Yes
Protein Tag
His Tag
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Shipping Condition
Dry Ice
Target Gene
mitogen-activated protein kinase
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Full Length, Recombinant, Inactive
Protein Subtype
Serine⁄Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.05mM EDTA, 0.05% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.