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BTK Recombinant Human Protein

Catalog number:  PV3363

Related applications:

Pharma & Biopharma

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Description

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_000052
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Protein Form: Full Length, Recombinant, Cytoplasmic
Research Category: Signal Transduction, Immunology
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry: BTK
Target Gene: Bruton agammaglobulinemia tyrosine kinase
Gene ID (Entrez): 695
Molecular Weight: 81.3 kDa
Quantity: 10μg
Protein Subtype: Cytoplasmic Tyrosine Kinases
Gene Alias: BTK, ATK, XLA
Validated Application: Kinase Assay
Protein Family: Kinases & Inhibitors
Expression System: Baculovirus
KinaseFamily: TEC Kinase Family
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.05% Triton X-100, 4 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.