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Thermo Scientific™

ErbB4 (HER4)

Catalog number:  PV3626

Related applications:

Oncology & Genetic Disease Research

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Description

Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3. ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_005226
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Mass: 10 µg
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™
Tag Position: N-Terminal
Target Entry: ERBB4
Target Gene: v-erb-a erythroblastic leukemia viral oncogene homolog 4
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic
Protein Subtype: Receptor Tyrosine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 2066
Molecular Weight: 61.6 kDa
Gene Alias: ErbB4 (HER4)
KinaseFamily: EGF Receptor (ErbB) Kinase Family
Protein Length: aa 708-993
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.