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RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein

Catalog number: PV3805

RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein

Catalog number: PV3805
Catalog Number
PV3805
Unit Size
10 µg
Price (USD)
453.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,542.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV380510 µg
453.00
Your Price:
***
PV40461 mg
6,570.00
Your Price:
***
PR7307A100 µg
1,542.00
Your Price:
***
Product Overview
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Additional Information
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RAF1 (cRAF) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylates and activates the serine⁄threonine specific protein kinases ERK1 and ERK2. The RAF1 Y340D Y341D mutant is constitutively active.

Specifications

Accession Number
NP_002871, Y340D, Y341D
Assay Entry
Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
Target Entry
RAF1 (cRAF) Y340D Y341D
Target Gene
v-raf-1 murine leukemia viral oncogene homolog 1
Expression System
Baculovirus
Form
Liquid
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Catalytic
Protein Subtype
Serine⁄Threonine Kinases
Research Category
Signal Transduction
Species
Human
Validated Application
Kinase Assay
Gene ID (Entrez)
4773, 5894
Molecular Weight
66.4 kDa
Quantity
10μg
Gene Alias
RAF1 (cRAF) Y340D Y341D
KinaseFamily
RAF Kinase Family
Protein Length
aa 306-648; Y340D, Y341D
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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Frequently asked questions (FAQs)

Citations & References