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IKBKB (IKK Beta) Recombinant Human Protein

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Description

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_001547
Expression: Baculovirus
Gene Aliases: IKBKB (IKK Beta)
Gene ID: 3551, 4088
Kinase Family: IKK Kinase Family
Kinase Group: Ser⁄Thr Kinases: Other
Molecular Weight: 114 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Form: Full Length,Recombinant
Protein Subtype: Serine⁄Threonine Kinases
Protein Tag or Fusion: GST Tag
Research Category: Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody,LanthaScreen® Substrate,Omnia® Bulk Substrate,Z'-LYTE™
Target Gene: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Validated Application: Kinase Assay

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.