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Thermo Scientific™

PDGFRA [T674I] Recombinant Human Protein

Catalog number:  PV3847

Related applications:

Protein Assays and Analysis

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Description

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA T674I is a Gleevec resistant form of PDGFRA.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_006197, T674T
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry: PDGFRA T674I
Target Gene: platelet-derived growth factor receptor, alpha polypeptide
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic
Protein Subtype: Receptor Tyrosine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 5156
Molecular Weight: 89.8 kDa
Gene Alias: PDGFRA T674I, PDGFR alpha
KinaseFamily: PDGFR Kinase Family
Protein Length: aa 550-1089; T674I
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.